Therefore, leading companies such as CRISPR Therapeutics, Intellia Therapeutics, or Editas Medicine might catch the eye of large pharmaceutical companies trying to step into this field and complement their pipeline with CRISPR/Cas9 technology. Shanthi is a contributor to InvestorPlace.com as well as a staff writer with Benzinga. Sold ATS Medical, Inc. to Medronics Inc. (MDT): Mr. Nohra served on the Board of Directors of ATS Medical, Inc. Medronics bought out ATS Medical for $370M. Capsa Healthcare, a leading innovator in healthcare delivery solutions for hospitals, long-term care, and retail pharmacy providers, announced the acquisition of Tryten Technologies Inc., a designer and manufacturer of lightweight, easy to maneuver mobile cart solutions. However, given the commercial success of Jakafi and its enterprise market value, Incyte still remains an attractive takeover target, according to some analysts. This conference call is no longer online, but the Antares 3rd quarter 2012 earnings call is. 2. The results of one of biotech's most polarizing clinical trials, an Alnylam Pharmaceuticals study in a rare disease known as transthyretin amyloidosis cardiomyopathy, are expected imminently. Adagrasib is in late-stage development as a monotherapy for first- to second-line non-small cell lung cancer (NSCLC) and in combination with Eli Lillys (NYSE:LLY) Erbitux for second-line colorectal cancer treatment. Stay on top of what's happening at JPM. And there are often rumors of other deals that never materialize. Total consideration can reflect both cash and equity offered upfront in exchange for the acquired companys shares, but deals in which the upfront payment was not specified, or was less than $50 million, were not included. Aesther Healthcare Acquisition Corp (NASDAQ: AEHA) Announces Filing of Definitive Proxy Statement with SEC in Connection with its Proposed Business Combination with Ocean Biomedical, Inc. Capsa Healthcare Acquires Tryten Technologies to Strengthen Its Leadership Position in Mobile Computing. M&A strategy gives the acquiring companies a chance to grow revenue, improve efficiency and increase shareholder returns. Keep track of M&A as it happens with this database. It is focused on developing transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. I have no business relationship with any company whose stock is mentioned in this article. But I think there's also a good fit on Seagen's pipeline too. *Average returns of all recommendations since inception. Alnylam currently carries a Zacks Rank #3 (Hold). Meanwhile, earlier this month, U.K.-based Elliott Advisors, one of the largest stakeholders in Alexion, urged the company to take a proactive approach and put itself up for sale to maximize the chance of an optimal outcome. In 2013, there were reports that Roche was eyeing BioMarin for a possible acquisition. *Stock Advisor returns as of September 17, 2021. Invest better with The Motley Fool. Biotech M&A - 2021 Deals Search for: Biotech M&A - 2021 Deals. 1985 - 2023 BioSpace.com. Subscribe to BioPharma Dive. Analysts, on average, see scope for about 90% upside for Mirati stock. Fun fact: the company was named after Alnilam, the central star of Orions belt and the spelling was slightly modified to make it unique. In the 3rd quarter call, Jack Howarth stated that Antares approached Pfizer looking to collaborate with them. In the business of drug development, deals can be just as important as scientific breakthroughs. Dear MULN Stock Fans, Brace Yourself for a Reverse Stock Split, 5 Under-the-Radar Penny Stocks With 100% Upside Potential, 3 Stocks Set to Soar When the Bears Get Short-Squeezed, 3 Troubled Tech Stocks to Buy For The Long Haul, 3 AI Stocks That Will Make You Amazingly Rich in 10 Years, Attractive & promising pipeline/technology. Even with a market cap of over $2B, we feel Acadia could fetch as much as $6B if the FDA approves pimavanserin, which could happen in the next 6 to 8 months. In the wake of generic drugs eating into the sales of off-patent branded drugs, growing pressure from regulators to reduce the prices of drugs, drying pipelines, and ever-increasing R&D costs, there has been an increasing consolidation within the drug industry. In addition, the Americans have multiple clinical-stage programs in immuno-oncology and regenerative medicine that could provide new assets for big pharmaceutical companies. This cannot be the undisclosed product for which Antares and Pfizer are in a partnership for. BioSpace is covering all the key announcements all week. Equipped with a Bachelors degree in Agriculture and an MBA with specialization in finance and marketing, she has about two decades of experience in financial reporting and analysis, and specializes in the biopharma and EV sectors. Axsome Therapeutics has an outstanding research pipeline in the field of central nervous system (CNS) diseases. PwC also expects large-sized deals, valued at $50 billion or more, for diversifying into adjacent therapeutic areas. At the time, I was . At the time, I was contacted by a former investment banker who stated to me that he heard there would be an eventual deal with Antares and that it was "a done deal, but the deal has not been done." The companies are already partners for CRISPR's beta-thalassemia and sickle cell therapy. There were a few, but not as many. Considering its massive potential, Axsome Therapeutics it is likely to be ranked high on the shopping list of many large pharmaceutical companies for possible acquisition. If you have an ad-blocker enabled you may be blocked from proceeding. Here's the Stock to Buy Now, Join Nearly 1 Million Premium Members And Get More In-Depth Stock Guidance and Research, Motley Fool Issues Rare All In Buy Alert, Copyright, Trademark and Patent Information. Someone is "mistaken" here. The quest behind the drive is to fill potential gaps in the pipeline. They are my opinions only. The pipeline progress has been encouraging. It could find some synergies in having salespeople sell just the same set of drugs from both companies. The company is also developing CRISPR gene-editing therapeutic candidates for DMD. Alexion Pharmaceuticals. Now, it is three years since the PARP inhibitor has been approved. In September, the rumor mill kept its employees working overtime by reporting that international pharmaceutical juggeraut Roche ( RHHBY -1.10%) was trying to arrange $15 billion in financing to. For those with multiple focuses, the chosen therapeutic area is based on lead asset or, lacking one that's distinctly identified, the company is classified under "other.". *Average returns of all recommendations since inception. Making the world smarter, happier, and richer. In early 2017, the rumor mill was spinning with whispers of Gilead (GILD) close to acquiring Incyte. This submission marks the first marketing application submission for a gene therapy product for any type of hemophilia. The stock has rallied from a little over $1 a share to a current price of $28.84, which represents an increase of over 2800% - a staggering number. Keith Speights: Let's switch gears. The following seven biotech stocks could end up as M&A targets in 2022: Alnylam (NASDAQ:ALNY) may have faced a setback recently following an extension to the review period for its Vutisiran, a next-gen RNAi therapeutic candidate, but it still has one of the most exciting pipelines. We'll see if that happens, but I think it would be one of the top megamerger acquisition candidates that are on the market right now. Immuno-oncology biotech Iovance Biotherapeutics' shares rocketed up by nearly 40% Tuesday on buyout chatter. Pharma under the microscope as FTC considers new ways to review acquisitions, 10 clinical trials to watch in the first half of 2023, Leap Therapeutics to buy Flame Biosciences in all-stock deal, JPM23: Vaccine developers as dealmakers, Gileads trial tea leaves and building platform companies, Trio of biotech buyouts jumpstarts J.P. Morgan healthcare meeting, Ensoma buys a startup to advance in vivo cell therapy work. When the symbol you want to add appears, add it to Watchlist by selecting it and pressing Enter/Return. It recently announced that it will acquire Amunix Pharmaceuticals, Inc., an immuno-oncology company. Just briefly, very quickly, I think Biogen (BIIB 0.54%) needs to make an acquisition -- ticker for Biogen is BIIB. Scott has had the most success in trading/investing in smaller cap growth companies. 5 min read Mergers & acquisitions (M&A) are back in focus in the biotech sector after a tepid run in the last couple of years. Youre reading a free article with opinions that may differ from The Motley Fools Premium Investing Services. But following Gilead's decision to acquire Kite Pharma in August of that year, the rumors died down. Tripos International bought out Pharsight for $57M. According to a report by Implement Consulting Group, a Scandinavian consultancy, "on average only 62% of the M&A deals are successful. Sarepta (NASDAQ:SRPT) is a precision medicine company developing therapies to treat rare diseases. M&A deal flow dwindled in 2021, reflecting stricter antitrust laws. Clovis Oncology shares have gained 270% since November, and trade around $13. All rights reserved. With focus on discovery, development and commercialization of a strong product portfolio, collaborating with industry-leading partners such as Novartis and Sanofi Genzyme, and an outstanding therapeutics pipeline, Alnylam is one of those biotech gems big pharma companies have on their radar. BMRN briefly touched $100.13 on February 5, 2019. Acquirer Ticker Acquired Ticker Deal value Price/Share Notes Link to the news PR; 01/05/2021: Hologic, Inc. HOLX: Private-German co. $64M-leader in biopsy site markers: https://bwnews.pr/2L3d7lF: CTX001 is being developed in collaboration with Vertex Pharmaceuticals Incorporated. (Source: EY 2019 M&A Firepower Report) 1. There would be some synergies on the commercial sales side. The mergers and acquisitions included in the database are limited by certain criteria, namely that they must be for an entire company not for product licensings, options to acquire or for partial equity stakes. Analysts, on average, predict over 75% upside for Crispr shares. Politics. If there's anything we've missed, or any additional information you'd like to see, please reach out and let us know. Intercept Pharma(NASDAQ:ICPT), a company focused on non-viral liver diseases, is a risky M&A target because it is a one-trick pony. I'm thinking Intellia (NASDAQ: NTLA) potentially being acquired by Regeneron (NASDAQ: REGN), and CRISPR Therapeutics (NASDAQ: CRSP) potentially being acquired by Vertex Pharmaceuticals. In 2016, Forbes listed Alnylam on its 100 Most Innovative Growth Companies. Additionally, it has a robust gene therapy pipeline, targeting DMD, limb-girdle muscular dystrophies and several other indications. It was also approved in the EU. Johnson & Johnson merged with ALZA Corporation for a $10.5B stock for stock transaction. You can see the complete list of todays Zacks #1 Rank (Strong Buy) stocks here. BioNTech SE (Nasdaq: BNTX, "BioNTech") and InstaDeep Ltd. ("InstaDeep") today announced that they have entered into an agreement under which BioNTech will acquire InstaDeep, a leading global technology company in the field of artificial intelligence ("AI") and machine learning ("ML"). Abbott Laboratories bought out Solvay Pharmaceuticals for $6.1B. I also agree with you that Vertex, if there's going to be one of those massive big pharma mergers like we've seen over the last 20 years, some of those massive deals, I think Vertex would be an excellent candidate to be acquired by a bigger company. The downside is that I'm not really sure Vertex wants to get into the CAR-T business, which is basically the other half of CRISPR's clinical pipeline. 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